SARS-CoV-2 update II
Our map of SARS-CoV-2 motif-based interactions finally published in Nat Com: https://www.nature.com/articles/s41467-021-26498-z
Caroline Benz’s “behind the paper” blog tells how it all started: https://bioengineeringcommunity.nature.com/posts/how-does-sars-cov-2-hijack-the-human-cell
SARS-CoV-2 update I
Happy to release our results on the large-scale discovery of the motif-based interactions of coronavirus.
The second generation human disorderome
Delighted to finally release the second generation human disorderome. Together with Davey lab we describe an optimized phage library that allows the screening of ~1,000,000 overlapping peptides in a single binding assay, PepTools for annotations of peptide hits and over 2,000 SLiM-based interactions.
New year – new postdoc position for a wet lab biochemist availabe in the lab, in a project aimed to investigate how Sars-CoV2 interacts with host factors. More information and application here:
We produly present Dr Muhammad Ali, the second PhD from the lab, after an excellent PhD thesis defense with Prof. Shoshana Wodak as faculty opponent.
BioRxiv relese: Cytoplasmic short linear motifs in ACE2 and integrin beta3 link SARS-CoV-2 host cell receptors to endocytosis and autophagy (http://disq.us/t/3s3p4zg)
Ready to take on Sars-CoV-2 together with the rest of the SSF funded team.
We are looking for up to two new protein-loving PhDs students to join the lab in August 2020.
See https://ubimotif.ku.dk/ for more info.
COVID-19 apart, March has been a fabulous month. Congrats to Susanne Luchow and Caroline Benz for their fabulous 50% PhD seminars. Awesom that we still have two years to do science together!
Happy with the successful Tiselius 2019 symposium (https://tiseliussymposium.org/). Many thanks to all speakers and participants!
Welcoming Dr. Andreas Lange (visting postdoc with EMBO short-term fellowship) and Dr. Ahmed Sayadi (researcher) to the group.
Great time hanging out with Eszter and Caroline at the Affinity 2019 meeting, not to mention sharing session with Dr Sidhu.
Congratulations to Kalle N for a well defended Master thesis!
Co-organized the first soapbox science event in Uppsala. Eszter Kassa told the crowd about our SSF funded host-pathogen project, with the support of Caroline Benz.
Our collaboration with the Cyert lab on calcineurin is now available on biorxiv:
Welcome to Johanna Kliche who is joining the group as a PhD student!
Welcoming Christin Kossman & Anna Bonhoure as visiting PhD students.
Congratulations to Dr. Gustav Sundell – well defended! Proud to present the first Dr from the lab!
Ivarsson lab members at the EMBO workshop on the Modularity of Signaling Proteins and Networks (http://meetings.embo.org/event/18-modularity; photos by Toby Gibson)
September 12, 2018
Celebrating Gustav’s masterpiece (http://msb.embopress.org/content/14/8/e8129.long) with cake (and some bubbles).
Welcome to the “new home” of the lab!
The lab has passed the first critical start-up years and is now going into the next phase with fresh funding and new people. What can be more fitting than celebrating this with a new webpage?! The next years we will continue charting human protein-protein interactions that rely on short linear motifs. We will also take on the challenge of exploring host-pathogen protein-protein interactions on large scale. The adventure continues!