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Updates from the Ivarsson lab

We have an open postdoc position (application deadline August 22), check it out here:

https://www.uu.se/en/about-uu/join-us/details/?positionId=525337

June 2022

Delighted to release Johanna Kliche’s manuscript on large-scale identification oh phospho-modulated interactions

https://www.biorxiv.org/content/10.1101/2022.06.08.495335v1

Also very happy to share our large-scale panviral analysis of SLiM-based hijacking by Mihalic et al

https://www.biorxiv.org/content/10.1101/2022.06.19.496705v1

November 2021

SARS-CoV-2 update II

Our map of SARS-CoV-2 motif-based interactions finally published in Nat Com: https://www.nature.com/articles/s41467-021-26498-z

Caroline Benz’s “behind the paper” blog tells how it all started: https://bioengineeringcommunity.nature.com/posts/how-does-sars-cov-2-hijack-the-human-cell

April 2021

SARS-CoV-2 update I

Happy to release our results on the large-scale discovery of the motif-based interactions of coronavirus.

https://www.biorxiv.org/content/10.1101/2021.04.19.440086v1

The second generation human disorderome

Delighted to finally release the second generation human disorderome. Together with Davey lab we describe an optimized phage library that allows the screening of ~1,000,000 overlapping peptides in a single binding assay, PepTools for annotations of peptide hits and over 2,000 SLiM-based interactions.

https://www.biorxiv.org/content/10.1101/2021.04.13.439572v1

January 2021

New year – new postdoc position for a wet lab biochemist availabe in the lab, in a project aimed to investigate how Sars-CoV2 interacts with host factors. More information and application here:

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December 2020

We produly present  Dr Muhammad Ali, the second PhD from the lab, after an excellent PhD thesis defense with Prof. Shoshana Wodak as faculty opponent.

October 2020

BioRxiv relese: Cytoplasmic short linear motifs in ACE2 and integrin beta3 link SARS-CoV-2 host cell receptors to endocytosis and autophagy (http://disq.us/t/3s3p4zg)

August 2020

Our Sars-CoV-2 related plasmids for recombinant protein expression and purification are now available on Addgene addgene.org/Ylva_Ivarsson/

April 2020

Ready to take on Sars-CoV-2 together with the rest of the SSF funded team.

CarolineBenz_YlvaIvarsson2

March 2020

We are looking for up to two new protein-loving PhDs students to join the lab in August 2020.

See https://ubimotif.ku.dk/ for more info.

Apply here:

https://www.uu.se/en/about-uu/join-us/details/?positionId=323549

March 2020

COVID-19 apart, March has been a fabulous month. Congrats to Susanne Luchow and Caroline Benz for their fabulous 50% PhD seminars.  Awesom that we still have two years to do science together!

August 2019

Happy with the successful Tiselius 2019 symposium (https://tiseliussymposium.org/). Many thanks to all speakers and participants!

Welcoming Dr. Andreas Lange (visting postdoc with EMBO short-term fellowship) and Dr. Ahmed Sayadi (researcher) to the group.

June 2019

Great time hanging out with Eszter and Caroline at the Affinity 2019 meeting, not to mention sharing session with Dr Sidhu.

June 2019

Congratulations to Kalle N for a well defended Master thesis!

May 2019

Co-organized the first soapbox science event in Uppsala. Eszter Kassa told the crowd about our SSF funded host-pathogen project, with the support of Caroline Benz.

May 2019

Our collaboration with the Cyert lab on calcineurin is now available on biorxiv:

https://www.biorxiv.org/content/10.1101/632547v1#disqus_thread

February 2019

Welcome to Johanna Kliche who is joining the group as a PhD student!

Welcoming Christin Kossman & Anna Bonhoure as visiting PhD students.

October 2018

Congratulations to Dr. Gustav Sundell –  well defended!  Proud to present the first Dr from the lab!

September 2018

Ivarsson lab members at the EMBO workshop on the Modularity of Signaling Proteins and Networks (http://meetings.embo.org/event/18-modularity; photos by Toby Gibson)

September 12, 2018

Celebrating Gustav’s masterpiece (http://msb.embopress.org/content/14/8/e8129.long) with cake (and some bubbles).

Welcome to the “new home” of the lab!

The lab has passed the first critical start-up years and is now going into the next phase with fresh funding and new people. What can be more fitting than celebrating this with a new webpage?! The next years we will continue charting human protein-protein interactions that rely on short linear motifs. We will also take on the challenge of exploring host-pathogen protein-protein interactions on large scale.  The adventure continues!